Phytochemical analysis of high value medicinal plant Valeriana jatamansi using LC-MS and it's in-vitro anti-proliferative screening
نویسندگان
چکیده
منابع مشابه
Valepotriates Content Variation and Genetic Diversity in High Value Medicinal Herb, Valeriana jatamansi
Valeriana jatamansi is an important medicinal herb from Caprifoliaceae family found in the Himalayan region at an altitude of 1500-3600 m. It is known for its medicinal compounds Velerenic acid and Valepotriates. It is recommended for the treatment of insomnia, stimulates the central nervous system, and reduces spasms and anxiety. The aim of the present study was to study genetic diversity in t...
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OBJECTIVE This work aimed to investigate the anti-epileptic effects of valepotriate isolated from Valeriana jatamansi Jones and studied its possible mechanisms. METHODS The anti-epileptic effects of valepotriate were studied using maximal electroshock-induced seizure (MES), pentylenetetrazole (PTZ)-induced epilepsy, and pentobarbital sodium-induced sleeping model in mice. The possible anti-ep...
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Background: To study the anticancer activity of Plantago major, ethanolic, methanolic and acetonic extracts were assessed on HCT116, SW480 and HEK-293 as control. Methods: The cytotoxic activity, biocompatibility and toxicity tests were evaluated by MTT assay, hemolysis and Artemia salina - LD50 (on mice) tests, respectively. The analysis of essential oil compounds was performed by GC-MS analys...
متن کاملStandardization and Preliminary Phytochemical Screening of Nardostachys Jatamansi Dc. Rhizome
The plant Nardostachys jatamansi DC. (Valerianaceae) is a critically endangered rhizome bearing medicinal herb. It is restricted to specialized habitats in high altitudes of Himalaya ranging from 3000 to 5000m. Nardostachys jatamansi has been traditionally employed in treatment of wide range of disorders including nervous system, digestive system, circulatory system, respiratory system, urinary...
متن کاملAntioxidant, Biomolecule Oxidation Protective Activities of Nardostachys jatamansi DC and Its Phytochemical Analysis by RP-HPLC and GC-MS
The study aimed at analyzing the metabolite profile of Nardostachys jatamansi using RP-HPLC, GC-MS and also its antioxidant, biomolecule protective and cytoprotective properties. The 70% ethanolic extract of Nardostachys jatamansi (NJE) showed the presence of polyphenols and flavonoids (gallic acid, catechin, chlorogenic acid, homovanillin, epicatechin, rutin hydrate and quercetin-3-rhamnoside)...
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ژورنال
عنوان ژورنال: Phytomedicine Plus
سال: 2021
ISSN: 2667-0313
DOI: 10.1016/j.phyplu.2021.100025